Forced Maneuvers

Similar to spirometry in cooperative humans, Buxco's Forced Maneuvers systems provide comprehensive pulmonary function data for preclinical applications. The systems – available for mouse, rat/guinea pig, and larger subjects – are highly-automated and include all necessary hardware and software.

For the FRC maneuver, subjects must be spontaneously-breathing. For other maneuvers, subjects may be ventilated (ventilator included) or spontaneously-breathing. Subjects are anesthetized.


Control panel and pressure/vacuum reservoirs Chambers for rat/guinea pig and mouse

Available maneuvers

  • Resistance and Dynamic Compliance
  • Boyle's Law FRC
  • Fast Flow Volume
  • Quasistatic Pressure Volume
  • DLCO and Multi-breath DLCO (except mouse)

Features

  • Preferred system for COPD research
  • Software-driven system, highly-automated
  • Fast-response valving, low dead space
  • Complete a series of maneuvers in just minutes
  • Determine FRC and other lung capacities
  • Software reports FEV(x), FEF(x) and many other values
  • Ability to study small rodents - even mice
  • Direct measurement of lung resistance and dynamic compliance
  • View results immediately, use overlays to compare repeated maneuvers

For more information, see Pulmonary Function Testing.

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